5,315 research outputs found

    Southern Disclosure: One Southern-and-Queer Middle School Teacher’s Narrative

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    This narrative inquiry is an autoethnographical account of one queer-identified middle school teacher\u27s career trajectory in the southern United States, and his struggle to navigate disclosure of his identity to students. Using a qualitative lens, the authors provide reasoning for the importance of middle school educators to have the ability to disclose their identities to students in order to cultivate an environment that is receptive to LGBTQ+ adolescents

    Kinetics of diffusional droplet growth in a liquid/liquid two-phase system

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    This report contains experimental results for the interdiffusion coefficient of the system, succinonitrile plus water, at a number of compositions and temperatures in the single phase region of the phase diagram. The concentration and temperature dependence of the measured diffusion coefficient has been analyzed in terms of Landau - Ginzburg theory, which assumes that the Gibb free energy is an analytic function of its variables, and can be expanded in a Taylor series about any point in the phase diagram. At most points in the single phase region this is adequate. Near the consolute point (critical point of solution), however, the free energy is non-analytic, and the Landau - Ginzburg theory fails. The solution to this problem dictates that the Landau - Ginzburg form of the free energy be replaced by Widom scaling functions with irrational values for the scaling exponents. As our measurements of the diffusion coefficient near the critical point reflect this non-analytic character, we are preparing for publication in a refereed journal a separate analysis of some of the data contained herein as well as some additional measurements we have just completed. When published, reprints of this article will be furnished to NASA

    Implementation of liquid culture for tuberculosis diagnosis in a remote setting: lessons learned.

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    Although sputum smear microscopy is the primary method for tuberculosis (TB) diagnosis in low-resource settings, it has low sensitivity. The World Health Organization recommends the use of liquid culture techniques for TB diagnosis and drug susceptibility testing in low- and middle-income countries. An evaluation of samples from southern Sudan found that culture was able to detect cases of active pulmonary TB and extra-pulmonary TB missed by conventional smear microscopy. However, the long delays involved in obtaining culture results meant that they were usually not clinically useful, and high rates of non-tuberculous mycobacteria isolation made interpretation of results difficult. Improvements in diagnostic capacity and rapid speciation facilities, either on-site or through a local reference laboratory, are crucial

    Investigation of Sulfur Cycling in Marine Sponge Cinachyrella spp. from a South Florida Reef

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    Symbionts within marine sponges are actively participating in the biogeochemical cycles. Among them, the role of symbiont microbes in the sulfur cycle remains a mystery. This study measured the abundance of microbes within the genus Cinachyrella before and after exposure to hydrogen sulfide. A four-part study was conducted: a) five-hour drop experiments, b) vertical distribution experiments, c) five-hour uptake experiments, and d) long-term exposure experiments. The five-hour drop experiment utilized a microsensor to measure sulfide levels, which was lowered 1.0 mm every thirty minutes for a total of 5 hours. Three trials were performed, each with one sponge and a control with no sponge. The vertical distribution experiments measured hydrogen sulfide levels throughout 9.0 mm. A five-hour uptake experiment measured hydrogen sulfide over five hours without the use of microsensors. The bacterial composition was detailed during long-term exposure experiments, where three sponges were exposed to 60 μmol/L for several weeks. Tissue samples collected from the long-term exposure experiment underwent microbial DNA extractions and high-throughput sequencing. Hydrogen sulfide concentrations from the five-hour drop, vertical-distribution, and five-hour experiments underwent various generalized additive models and generalized linear models. A significant relationship between time (depth for the vertical-distribution) and hydrogen sulfide concentration (p-valueDraconibacterium, family Rhodobacteraceae, and genus Halodesulfovibrio within sponges. These data suggest that Cinachyrella spp. can filter and process hydrogen sulfide from the water column with help from its microbiome

    Earnouts: A Study of Financial Contracting in Acquisition Agreements

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    We empirically examine earnout contracts, which provide for contingent payments in acquisition agreements. Our analysis reveals considerable heterogeneity in the terms of earnout contracts, i.e. the potential size of the earnout, the performance measure on which the contingent payment is based, the period over which performance is measured, the frequency with which performance is measured, and the form of payment for the earnout. Consistent with the costly contracting hypothesis, we find that the terms of earnout contracts are associated with measures of target valuation uncertainty, target growth opportunities, and the degree of post-acquisition integration between target and acquirer. We conclude that earnouts are structured to minimize the costs of adverse selection and moral hazard in acquisition negotiations.

    The locus of action in trialkyl tin compounds in yeast mitochondria

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    Trialkyl tin compounds have been shown to be potent inhibitors of the yeast mitochondrial OS-ATPase complex in both the membrane bound form and purified soluble preparation. Binding studies with 11^Sn labelled triethyl tin have shown that the inhibitory properties of triethyl tin are due to the presence of a high affinity binding site which is not competed for by oligomycin or venturicidin. Die concent­ration of the binding site in the purified enzyme is 6mole/mole enzyme, the binding site has been shown to be located on the FQ component of the OS-ATPase complex. A new radioactive affinity label (DBCT) for trialkyl tin compounds has been synthesized, binding experiments revealed that DBCT is a covalent inhibitor of the OS-ATPase. Extraction and isolation experi­ments have shown that DBCT binds to a small lipophilic, apparently non-protein component of the mitochondrial membrane. The significance of these findings are discussed in relation to current ideas on oxidative phosphorylation. A biochemical genetic study has shown that triethyl tin may have another mode of action which is related to the transport of Adn nucleotides across the mitochondrial membrane

    Fast transcription of unstructured audio recordings

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    URL to conference session list. Title is under heading: Wed-Ses1-P1: Phonetics, Phonology, cross-language comparisons, pathologyWe introduce a new method for human-machine collaborative speech transcription that is significantly faster than existing transcription methods. In this approach, automatic audio processing algorithms are used to robustly detect speech in audio recordings and split speech into short, easy to transcribe segments. Sequences of speech segments are loaded into a transcription interface that enables a human transcriber to simply listen and type, obviating the need for manually finding and segmenting speech or explicitly controlling audio playback. As a result, playback stays synchronized to the transcriber's speed of transcription. In evaluations using naturalistic audio recordings made in everyday home situations, the new method is up to 6 times faster than other popular transcription tools while preserving transcription quality

    Reading Disorders

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    There are two major types of reading disorder; developmental dyslexia and reading comprehension impairment. The primary difficulty in dyslexia is with the accurate and fluent reading of single words, whilst in reading comprehension impairment words can be read accurately but there is no or little understanding of what is read. Using the causal modelling framework, the underlying causes of the two disorders are reviewed together with the co-occurrence of reading and language disorders. The rationale for viewing reading as a dimensional disorder, where the difficulties experienced are on a continuum rather than using cut-off points to identify disorders is also reviewed
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